1. What do you think about antioxidantsas anticancer agents?It depends or I wouldlike to say No Idea, Anti-oxidants are neither be a anticancer nor be acarcinogenic the studies mentioned in the given papers failed to explain antioxidantsas carcinogenic agent. But some studies shown that antioxidants potentialanticancer agents and said that no action towards growing tumor.RationaleIn Volkan I sayin.et al.
tried to demonstrate that AntioxidantsAccelerate Lung Cancer Progression in Mice. But I think the in this studythe tumor is induced by promoting or overexpression tumor gene. Which is notexist in the nature.And Limitation in thisstudy, Mouse model will not demonstrate in human all the time.And my previous knowledgeis that antioxidants are nothing but vitamins which are naturally available. The book named as Cancer and Vitamin C, about vitamin C’s great potential as an anti- cancer agent by Linus Pauling.
As name suggestpotential not well-established facts. 2. What do you think Dr. Watson’smessage is?Completelybase less statement. RationaleAsanswered to first question its controversial debatable concept but due to lackof scientific efforts and current studies still failed to demonstrate whetherantioxidants are anticancer agent or not.
3. Who is wrong and who is right?No one. Jim Watson’s has not provided significant scientificexplanation about the issue. Volkan I sayin.
et al.tried to demonstrate that AntioxidantsAccelerate Lung Cancer Progression in Mice. But in there study model theyhave used the tumor cells are induced not naturally existed tumor. Previousknowledge is that no model or rare animal model exhibit tumor growth rate threetimes and this kind accelerated tumor growth we can’t see in nature it isnothing but over expression of tumor inducing factor.According to Lindahl, The tumours grew about three times fasterthan those in animals that did not receive the antioxidant.
Treated mice alsodied from their cancers about two times as quickly as untreated mice. Needsfurther interpretation.Therefore, given limitedarticle and there research work provides inadequate explanation to demonstratewhat they have stated. 4. Evaluate opinions versus facts inscientific reasoningVolkan I sayin.et al.
tried to demonstrate that AntioxidantsAccelerate Lung Cancer Progression in Mice. But in there study model theyhave used the tumor cells are induced not naturally existed tumor. Previousknowledge is that no model or rare animal model exhibit tumor growth rate threetimes and this kind accelerated tumor growth we can’t see in nature it isnothing but over expression of tumor inducing factor.The book named as Cancer and Vitamin C, about vitamin C’s great potential as an anti- cancer agent by Linus Pauling. As name suggestpotential not well-established facts. In paper 11, The animalmodel used which is aggressive. On another hand inactivation P53.
The maincourse question is that whether inactivation P53 is due to antioxidant ?inactivation P53 is due another factor that overexpressed due to genes/mutationused in animal model? have to know.In paper 11, talkingabout clinical trials about vitamin A and Vitamin E but further intervention required. Like on which population they haveconducted the prevalence of lung cancer in that population.
Has to considergenome factor of particular population. 5. Take notes andwrite a page report addressing your understanding of the impact ofantioxidants in cancer preventionBased on previousknowledge. Antioxidants are nothing but vitamin C and vitamin E. have vitalrole to maintain homeostasis.
Above mentioned vitamins playvital role in neutralizing in free radicals. Free radicals or reactive oxygen speciesare nothing but waste product left after metabolism in the body always carry avalency of electron and due to this valency free radical interact with anyproduct causes disruption of that molecule also damage to parts of cells such as proteins, DNA, and cellmembranes by stealing their electrons through a process called oxidation. Free radicals has potential causes cancer may lead to cancer. But notall the time. Free radicals or reactive oxygen species one of the risk factorthat will causes the cancer.
The condition is that caner is not only dependentof free radicals, cancer will induce in human by other etiological factors riskfactors.The antioxidants are nothing but electron acceptor binds with freeradical neutralizes it. Three by antioxidants potentially act as anti-canceragent.But there is very study conducted to demonstrate antioxidants arepotentially causes cancer.
And more study required to justify.1. Are antioxidants good for you?JUSTIFY your answerIt depends. If my body is possessing with more free radicals than I needantioxidant to rectify the problem. If my body is possessing with normal andhost system itself manage free radical in the body than no need ofantioxidants. Note: The given limited article are not significantly justifying antioxidantcould be anticancer agents.
Or not.But still need do more study to establish the statement cancer could betreated wit antioxidents
