An example of this is in a co-current flow setup, the product temperature is 10 to 20 °C below the air outlet temperature. Although during the drying process, the droplets could be exposed to high temperature, this exposure time is extremely short. The exposure time is usually in the range of milliseconds or seconds. Under these conditions, drug degradation is not anticipated.
The spray drying technique was conceived as a dehydration process used to prolong the lifespan of the product. At the same time, it has increasingly attracted the interest of scientists who wants to encapsulate drugs, extracts, aromatic oils, pigments, and flavors within different types of carriers such as polymeric nanoparticles (NPs), microparticles (MPs), and nanocomposite MPs.